PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy

@article{Cooper2006PASD1AD,
  title={PASD1, a DLBCL-associated cancer testis antigen and candidate for lymphoma immunotherapy},
  author={Christopher D. O. Cooper and Amanda P. Liggins and Kamel Ait-Tahar and Giovanna Roncador and Alison H Banham and Karen Pulford},
  journal={Leukemia},
  year={2006},
  volume={20},
  pages={2172-2174}
}
Despite advances in defining clinically relevant subtypes of diffuse large B-cell lymphoma (DLBCL), identifying high-risk patients and improved therapeutic options remains a priority. One approach is through the identification of tumor-associated antigens (TAAs), of which cancer testis antigens (CTAs) are of particular interest. Their restricted normal tissue expression, commonly widespread expression in tumors and immunogenicity makes them attractive therapeutic targets and markers for early… CONTINUE READING

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