PAS kinase promotes cell survival and growth through activation of Rho1.

Abstract

In Saccharomyces cerevisiae, phosphorylation of Ugp1 by either of the yeast PASK family protein kinases (yPASK), Psk1 or Psk2, directs this metabolic enzyme to deliver glucose to the periphery for synthesis of the cell wall. However, we isolated PSK1 and PSK2 in a high-copy suppressor screen of a temperature-sensitive mutant of target of rapamycin 2 (TOR2… (More)
DOI: 10.1126/scisignal.2002435

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@article{Cardon2012PASKP, title={PAS kinase promotes cell survival and growth through activation of Rho1.}, author={Caleb M Cardon and Thomas Beck and Michael N. Hall and Jared Rutter}, journal={Science signaling}, year={2012}, volume={5 209}, pages={ra9} }