PARS: a web server for the prediction of Protein Allosteric and Regulatory Sites

@article{Panjkovich2014PARSAW,
  title={PARS: a web server for the prediction of Protein Allosteric and Regulatory Sites},
  author={Alejandro Panjkovich and Xavier Daura},
  journal={Bioinformatics},
  year={2014},
  volume={30 9},
  pages={1314-5}
}
The regulation of protein activity is a key aspect of life at the molecular level. Unveiling its details is thus crucial to understanding signalling and metabolic pathways. The most common and powerful mechanism of protein-function regulation is allostery, which has been increasingly calling the attention of medicinal chemists due to its potential for the discovery of novel therapeutics. In this context, PARS is a simple and fast method that queries protein dynamics and structural conservation… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Similar Papers

Loading similar papers…