PARP-1--a Perpetrator of Apoptotic Cell Death?
@article{Chiarugi2002PARP1aPO, title={PARP-1--a Perpetrator of Apoptotic Cell Death?}, author={A. Chiarugi and M. A. Moskowitz}, journal={Science}, year={2002}, volume={297}, pages={200 - 201} }
The caspase-dependent pathway of programmed cell death has been well documented. In their Perspective,
Chiarugi and Moskowitz
report on new findings (
Yu
et al .) that reveal a caspase-independent pathway of apoptosis driven by the nuclear enzyme PARP-1.
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