PAR-1 is required for the maintenance of oocyte fate in Drosophila.

@article{Huynh2001PAR1IR,
  title={PAR-1 is required for the maintenance of oocyte fate in Drosophila.},
  author={Jean-Ren{\'e} Huynh and Joshua M Shulman and Richard Benton and Daniel St Johnston},
  journal={Development},
  year={2001},
  volume={128 7},
  pages={1201-9}
}
The PAR-1 kinase is required for the posterior localisation of the germline determinants in C. elegans and Drosophila, and localises to the posterior of the zygote and the oocyte in each case. We show that Drosophila PAR-1 is also required much earlier in oogenesis for the selection of one cell in a germline cyst to become the oocyte. Although the initial steps in oocyte determination are delayed, three markers for oocyte identity, the synaptonemal complex, the centrosomes and Orb protein… CONTINUE READING
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The polarisation of the anterior - posterior and dorsalventral axes during Drosophila oogenesis

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