PAQR3 plays a suppressive role in laryngeal squamous cell carcinoma

  title={PAQR3 plays a suppressive role in laryngeal squamous cell carcinoma},
  author={Qiang Wu and Kun Zhuang and Huijun Li},
  journal={Tumor Biology},
Laryngeal squamous cell carcinoma (LSCC) is a common type of head and neck malignancy worldwide. The molecular mechanism of LSCC remains not well understood. PAQR3 (progestin and AdipoQ receptors) is a member of the progestin and adipoQ receptor (PAQR) family. Many studies have showed that PAQR3 acts as a new tumor suppressor. However, its expression and functions in LSCC are still unknown. In our study, the expression of PAQR3 was downregulated in human LSCC tissues compared to that in… CONTINUE READING
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