PAPAVERINE IN THE PROPHYLAXIS OF MIGRAINE AND OTHER VASCULAR HEADACHE IN CHILDREN

@article{Sillanp1978PAPAVERINEIT,
  title={PAPAVERINE IN THE PROPHYLAXIS OF MIGRAINE AND OTHER VASCULAR HEADACHE IN CHILDREN},
  author={Matti Sillanp{\"a}{\"a} and Marjaana Koponen},
  journal={Acta P{\ae}diatrica},
  year={1978},
  volume={67}
}
ABSTRACT. A Daily dose of papaverine (5–10 mg per kg body weight) was administered on a double‐blind basis for two months to 42 successive child patients suffering from migraine or other vascular headache attacks not less than twice a month. Thirty‐seven patients received the drug for the whole period of two months and 31 of these could be followed for a period of one to 10 months (mean 4.5 months) after the cessation of the treatment. Nineteen received papaverine and 18 placebo. Six out of 19… 

Drug Treatment of Migraine in Children

Most of the drugs used in the treatment of migraine in children are well tolerated and without relevant adverse effects and in migraine prophylaxis, the most common adverse effects are drowsiness and bodyweight gain.

WITHDRAWN: Drugs for preventing migraine headaches in children.

  • S. VictorS. Ryan
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    The Cochrane database of systematic reviews
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The evidence from controlled trials on the efficacy and tolerability of pharmacological agents taken on a regular basis to prevent the occurrence of migraine attacks and/or reduce the intensity of such attacks in children with migraine was described and assessed.

Prophylactic Treatment of Migraine in Children. Part 1. A Systematic Review of non-Pharmacological Trials∗

A few non-pharmacological treatments such as relaxation may be effective as prophylactic treatment for migraine in children, and conclusions on effectiveness have to be drawn with caution.

Migraine in Children and Adolescents

According to recent literature, paracetamol (acetaminophen) and ibuprofen can be recommended for the acute treatment of migraine attacks in children and adolescents, and sumatriptan nasal spray can beRecommendations on the use of prophylactic drugs in paediatric patients are limited.

Placebo Efficacy in Childhood and Adolescence Migraine: An Analysis of Double-Blind and Placebo-Controlled Studies

Trial designs on the acute and prophylactic treatment of migraine in children and adolescents should consider the specific findings of this analysis in order to exhibit a higher probability of showing significant differences between placebo and verum drug.

Quality of Life and Psychological Functioning in Observational and Intervention Studies in Childhood Migraine

This thesis aims to investigate sleep deprivation as a potentially causative factor for headache attacks in childhood migraine, and to explore the effect of resting and sleeping after the start of the headache attack on headache symptoms.

Pharmacology of migraine.

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  • Psychology, Medicine
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This progress report will focus on the lines of evidence that have led to perturbed serotonergic neurotransmission as a putative mechanism of migraine.

Headaches in children.

  • B. Köhler
  • Medicine
    Ergebnisse der inneren Medizin und Kinderheilkunde
  • 1984
The management of a child with headache begins with a detailed history, followed by a thorough examination supported by appropriate laboratory investigations, and in few cases will general medical treatment be necessary.

Other Neurological Disorders

The role of vision in learning disorders and central nervous system manifestations of neurofibromatosis in children with learning disabilities are studied.

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SYNOPSIS

PROPRANOLOL USED IN PROPHYLAXIS OF MIGRAINE IN CHILDREN

Since propranolol does not cause serious side effects provided certain patients are excluded, it seems justifiable to recommend this preparation where prophylactic therapy is indicated in cases of severe and frequent migraine.

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