PALB2 mutations in German and Russian patients with bilateral breast cancer

  title={PALB2 mutations in German and Russian patients with bilateral breast cancer},
  author={Natalia Valerijevna Bogdanova and Anna P Sokolenko and Aglaya G. Iyevleva and Svetlana N. Abysheva and Magda A Blaut and Michael Bremer and Hans Christiansen and Margret Rave-Fr{\"a}nk and Thilo D{\"o}rk and Evgeny N. Imyanitov},
  booktitle={Breast Cancer Research and Treatment},
Since germline mutations in the PALB2 (Partner and Localizer of BRCA2) gene have been identified as breast cancer (BC) susceptibility alleles, the geographical spread and risks associated with PALB2 mutations are subject of intense investigation. Patients with bilateral breast cancer constitute a valuable group for genetic studies. We have thus scanned the whole coding region of PALB2 in a total of 203 German or Russian bilateral breast cancer patients using an approach based on high-resolution… CONTINUE READING
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