PAK1 is a novel cardiac protective signaling molecule

@article{Ke2014PAK1IA,
  title={PAK1 is a novel cardiac protective signaling molecule},
  author={Yunbo Ke and Xin Wang and Xuhui Jin and R. John Solaro and Ming Lei},
  journal={Frontiers of Medicine},
  year={2014},
  volume={8},
  pages={399-403}
}
We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinase 1 (PAK1), a member of a serine/threonine protein kinase family. Despite the large body of evidence from studies in noncardiac tissue indicating that PAK1 activity is key in the regulation of a number of cellular functions, the role of PAK1 in the heart has only been revealed over the past few years. In this review, we assemble an overview of the recent findings on PAK1 signaling in the heart… 

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