Corpus ID: 22980038

PAGE4 is a cytoplasmic protein that is expressed in normal prostate and in prostate cancers.

@article{Iavarone2002PAGE4IA,
  title={PAGE4 is a cytoplasmic protein that is expressed in normal prostate and in prostate cancers.},
  author={Carlo Iavarone and Curt D. Wolfgang and Vasantha Kumar and Paul Duray and Mark C. Willingham and Ira Pastan and Tapan Kumar Bera},
  journal={Molecular cancer therapeutics},
  year={2002},
  volume={1 5},
  pages={
          329-35
        }
}
  • Carlo Iavarone, Curt D. Wolfgang, +4 authors Tapan Kumar Bera
  • Published in Molecular cancer therapeutics 2002
  • Biology, Medicine
  • PAGE4 is an X chromosome-linked cancer-testis antigen that was identified by expressed sequence tags database mining and a functional genomic approach. PAGE4 is preferentially expressed in normal male and female reproductive tissues and also in a variety of cancers including prostate. In the present study, we have used in situ hybridization to show that PAGE4 mRNA is expressed only in the epithelial cells of normal and prostate-cancer specimens. Analysis of the protein product encoded by the… CONTINUE READING

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    Citations

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    Inflammation, prostatitis, proliferative inflammatory atrophy: 'Fertile ground' for prostate cancer development?

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    CITES BACKGROUND
    HIGHLY INFLUENCED

    PAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway

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