PACK-CXL: defining CXL for infectious keratitis.

  title={PACK-CXL: defining CXL for infectious keratitis.},
  author={Farhad Hafezi and J. Bradley Randleman},
  journal={Journal of refractive surgery},
  volume={30 7},
THE CONCEPT OF CXL In 1998, the proof-of-principle for corneal collagen cross-linking (CXL) was born from such a “simple” concept. Combining ultraviolet-A light and a chromophore (vitamin B2, riboflavin), the cornea could be stiffened within a mere half hour and progressive thinning diseases such as keratoconus could be halted.1,2 Although still considered a relatively new concept, CXL is now in clinical use worldwide. Cross-links in the cornea are not a technique, but rather a physiological… CONTINUE READING

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