PACE-1, a novel protein that interacts with the C-terminal domain of ezrin.

@article{Sullivan2003PACE1AN,
  title={PACE-1, a novel protein that interacts with the C-terminal domain of ezrin.},
  author={Alexandra Sullivan and C. R. Uff and Clare M. Isacke and Rick Francis Thorne},
  journal={Experimental cell research},
  year={2003},
  volume={284 2},
  pages={
          224-38
        }
}
The ERM proteins (ezrin, radixin, moesin) together with merlin comprise a subgroup of the band 4.1 superfamily. These proteins act as membrane cytoskeletal linker proteins mediating interactions between the cytoplasmic domains of transmembrane proteins and actin. To better understand how the ERM proteins function to regulate these junctional complexes, a yeast 2-hybrid screen was undertaken using ezrin as a bait. We describe here the identification and cloning of a novel protein, PACE-1, which… Expand
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