PACAP and VIP signaling in chondrogenesis and osteogenesis

  title={PACAP and VIP signaling in chondrogenesis and osteogenesis},
  author={T. Juh{\'a}sz and Solveig Lind Helgadottir and A. Tam{\'a}s and D. Reglodi and R. Z{\'a}k{\'a}ny},
  • T. Juhász, Solveig Lind Helgadottir, +2 authors R. Zákány
  • Published 2015
  • Biology, Medicine
  • Peptides
  • Skeletal development is a complex process regulated by multifactorial signaling cascades that govern proper tissue specific cell differentiation and matrix production. The influence of certain regulatory peptides on cartilage or bone development can be predicted but are not widely studied. In this review, we aimed to assemble and overview those signaling pathways which are modulated by PACAP and VIP neuropeptides and are involved in cartilage and bone formation. We discuss recent experimental… CONTINUE READING
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