PACAP and VIP signaling in chondrogenesis and osteogenesis

@article{Juhsz2015PACAPAV,
  title={PACAP and VIP signaling in chondrogenesis and osteogenesis},
  author={T. Juh{\'a}sz and Solveig Lind Helgadottir and A. Tam{\'a}s and D. Reglodi and R. Z{\'a}k{\'a}ny},
  journal={Peptides},
  year={2015},
  volume={66},
  pages={51-57}
}
  • T. Juhász, Solveig Lind Helgadottir, +2 authors R. Zákány
  • Published 2015
  • Biology, Medicine
  • Peptides
  • Skeletal development is a complex process regulated by multifactorial signaling cascades that govern proper tissue specific cell differentiation and matrix production. The influence of certain regulatory peptides on cartilage or bone development can be predicted but are not widely studied. In this review, we aimed to assemble and overview those signaling pathways which are modulated by PACAP and VIP neuropeptides and are involved in cartilage and bone formation. We discuss recent experimental… CONTINUE READING
    35 Citations
    Lack of Pituitary Adenylate Cyclase–Activating Polypeptide (PACAP) Disturbs Callus Formation
    • 4
    • PDF
    Signalling Alterations in Bones of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Gene Deficient Mice
    • 8
    • PDF
    Peripheral Nerve Fibers and Their Neurotransmitters in Osteoarthritis Pathology
    • 34
    • PDF
    Do Neuroendocrine Peptides and Their Receptors Qualify as Novel Therapeutic Targets in Osteoarthritis?
    • 15
    • PDF
    Age-related alterations of articular cartilage in pituitary adenylate cyclase–activating polypeptide (PACAP) gene–deficient mice
    • 6
    • PDF
    Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Reduces Oxidative and Mechanical Stress-Evoked Matrix Degradation in Chondrifying Cell Cultures
    • 13
    • PDF
    VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts
    • 11
    • PDF
    Altered Notch Signaling in Developing Molar Teeth of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)-Deficient Mice
    • 13

    References

    SHOWING 1-10 OF 104 REFERENCES
    A review of crosstalk between MAPK and Wnt signals and its impact on cartilage regeneration
    • 83
    The neuropeptide VIP regulates the expression of osteoclastogenic factors in osteoblasts
    • 23
    The control of chondrogenesis
    • 919
    Distinct VEGF Functions During Bone Development and Homeostasis
    • Yanqiu Liu, B. Olsen
    • Biology, Medicine
    • Archivum Immunologiae et Therapiae Experimentalis
    • 2014
    • 42
    • PDF
    Effects of Neuropeptides and Mechanical Loading on Bone Cell Resorption in Vitro
    • 31
    • PDF
    Bone tissue remodeling and development: focus on matrix metalloproteinase functions.
    • 114
    Roles of notch signalling in mandibular condylar cartilage.
    • 16