PA2800 Plays an Important Role in Both Antibiotic Susceptibility and Virulence in Pseudomonas aeruginosa

@article{Shen2012PA2800PA,
  title={PA2800 Plays an Important Role in Both Antibiotic Susceptibility and Virulence in Pseudomonas aeruginosa},
  author={Lixin Shen and Xiangli Gao and Jinhua Wei and Lin Chen and Xin Zhao and Bo Li and Kangmin Duan},
  journal={Current Microbiology},
  year={2012},
  volume={65},
  pages={601-609}
}
Pseudomonas aeruginosa is an important human pathogen which causes a variety of infections. P. aeruginosa infections are often difficult to treat due to the pathogen’s resistance to many antibiotics. Previously, it has been reported that a transposon insertion mutant in gene PA2800 of P. aeruginosa PAO1 was more sensitive to tetracycline and ciprofloxacin. Further characterization of this gene, a vacJ homolog, in this study indicated that this gene plays an important role in both antibiotic… CONTINUE READING
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