P9754 therapeutic intensification in non-metastatic osteosarcoma: A COG trial.


8514 Background: Outcome in osteosarcoma (OS) is predicted by percent necrosis (% NEC) after pre-operative chemotherapy. Efforts to improve outcome by post-operative therapeutic intensification have had limited success. Historically, 70% are standard responders (SR: < 98% NEC) whose outcomes justify efforts to intensify therapy. METHODS Patients <31 yrs… (More)


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