P75 nerve growth factor receptor staining is superior to S100 in identifying spindle cell and desmoplastic melanoma.

@article{Lazova2010P75NG,
  title={P75 nerve growth factor receptor staining is superior to S100 in identifying spindle cell and desmoplastic melanoma.},
  author={Rossitza Z Lazova and Iliana Tantcheva-Po{\'o}r and Alicia C Sigal},
  journal={Journal of the American Academy of Dermatology},
  year={2010},
  volume={63 5},
  pages={852-8}
}
BACKGROUND Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE We sought to compare the staining of p75 nerve growth factor receptor (NGF-R) and S100 in SCMs. METHODS We evaluated the staining of p75 NGF-R and S100 in 13 cases of SCMs: 3… CONTINUE READING

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