P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells.

@article{KaiHong2007P63EP,
  title={P63 expression pattern during rat epidermis morphogenesis and the role of p63 as a marker for epidermal stem cells.},
  author={Ji Kai-Hong and Xiong Jun and Hu Kai-Meng and Wang Ying and Liu Hou-Qi},
  journal={Journal of cutaneous pathology},
  year={2007},
  volume={34 2},
  pages={154-9}
}
BACKGROUND Recent evidence has suggested that p63 plays a particular role in maintaining the population of epidermal stem cells (ESCs), but the expression pattern of p63 during normal rat epidermis development is still unknown. We investigated the expression of p63 during development and differentiation of rat epidermis and identified whether p63 is a specific marker of rat ESCs cultured in vitro. METHODS Skin biopsies were obtained from embryonic day (E) 12 rat embryo, newborn, and 4-week… CONTINUE READING