P53 gene protein overexpression predicts results of trimodality therapy in esophageal cancer patients.


BACKGROUND P53 protein overexpression in esophageal cancer and its correlation with response and survival after chemoradiation was retrospectively investigated. METHODS Pretreatment and resection specimens were stained by automatic p53 immunohistochemical staining technique. RESULTS P53 was expressed in 84.0% of esophagoscopy (EGD) biopsies; 71.4% of… (More)


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