P53 gene polymorphisms and breast cancer risk in Arab women

@article{Alawadi2011P53GP,
  title={P53 gene polymorphisms and breast cancer risk in Arab women},
  author={S. Alawadi and L. Ghabreau and Mervat Alsaleh and Z. Abdulaziz and Mohamed Rafeek and N. Akil and M. Alkhalaf},
  journal={Medical Oncology},
  year={2011},
  volume={28},
  pages={709-715}
}
  • S. Alawadi, L. Ghabreau, +4 authors M. Alkhalaf
  • Published 2011
  • Medicine
  • Medical Oncology
    • The association between polymorphisms in the p53 tumor suppressor gene and breast cancer risk has been studied in many human populations with conflicting conclusions. However, similar studies in Arab women are not available, and the status of these polymorphisms in this ethnic population is not known. We investigated the status of four known p53 gene polymorphisms and their possible role in breast cancer risk in Arab women. Genotyping was performed for 288 breast cancer women and 188 controls… CONTINUE READING
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    References

    SHOWING 1-10 OF 33 REFERENCES
    Polymorphism of TP53 codon 72 showed no association with breast cancer in Iranian women.
    • 61
    • PDF
    Analysis of p53 Gene Polymorphisms and Protein Over-expression in Patients with Breast Cancer
    • 34
    p53 polymorphisms and haplotypes in breast cancer.
    • 211
    A p53 codon 72 polymorphism associated with prostate cancer development and progression in Japanese.
    • 55
    Intronic polymorphisms in TP53 indicate lymph node metastasis in breast cancer.
    • 29
    Association of p53 polymorphisms with breast cancer: a case-control study in Slovak population.
    • 18
    Association of polymorphism in MDM-2 and p53 genes with breast cancer risk in Indian women.
    • 55
    Importance of TP53 codon 72 and intron 3 duplication 16bp polymorphisms in prediction of susceptibility on breast cancer
    • 111
    • Highly Influential
    p53 genotypes and haplotypes associated with risk of breast cancer.
    • 43
    • Highly Influential
    The p53 Arg72Pro and Ins16bp polymorphisms and their haplotypes are not associated with breast cancer risk in BRCA-mutation negative familial cases.
    • 19
    • Highly Influential