P53 gene polymorphisms and breast cancer risk in Arab women

  title={P53 gene polymorphisms and breast cancer risk in Arab women},
  author={S. Alawadi and L. Ghabreau and Mervat Alsaleh and Z. Abdulaziz and Mohamed Rafeek and N. Akil and M. Alkhalaf},
  journal={Medical Oncology},
  • S. Alawadi, L. Ghabreau, +4 authors M. Alkhalaf
  • Published 2011
  • Medicine
  • Medical Oncology
  • The association between polymorphisms in the p53 tumor suppressor gene and breast cancer risk has been studied in many human populations with conflicting conclusions. However, similar studies in Arab women are not available, and the status of these polymorphisms in this ethnic population is not known. We investigated the status of four known p53 gene polymorphisms and their possible role in breast cancer risk in Arab women. Genotyping was performed for 288 breast cancer women and 188 controls… CONTINUE READING
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