P53 expression, DNA ploidy and S-phase cell fraction in operable locally advanced non-small-cell lung cancer.

@article{Costa1996P53ED,
  title={P53 expression, DNA ploidy and S-phase cell fraction in operable locally advanced non-small-cell lung cancer.},
  author={Alberto Rodr{\'i}guez Costa and Rosella Silvestrini and Claudia Mochen and Cosimo Lequaglie and Patrizia Boracchi and A. Faranda and Graziella Vessecchia and Gianni Ravasi},
  journal={British Journal of Cancer},
  year={1996},
  volume={73},
  pages={914 - 919}
}
The identification of biomarkers to complement pathological stage for a more accurate prognosis and help clinicians decide on treatment is still an open problem for patients with lung cancer. Expression of P53 protein was detected by an immunohistochemical approach using the monoclonal antibody PAb1801 on paraffin-embedded sections of tumours obtained surgically from 102 stage II - IIIa patients with non-small-cell lung cancer (52 squamous cell carcinomas, 50 adenocarcinomas). [3H]Thymidine… CONTINUE READING

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