P458-1: Preventing gastrointestinal damage by monitoring patients with high risk medication

@article{Vries2014P4581PG,
  title={P458-1: Preventing gastrointestinal damage by monitoring patients with high risk medication},
  author={M. D. Vries and C. D. Linssen-Schuurmans and R. Rahman and H. S. Lau},
  journal={European Geriatric Medicine},
  year={2014},
  volume={5}
}
Materials and Methods: This prospective study analyzed the data of 53 older patients naive to strong opioids, and presenting with chronic pain of moderate to severe intensity. Patients were prescribed a 28-day treatment with PR OXN. In case of insufficient analgesia, the initial daily dose of PR OXN (10/5mg) could be gradually increased. The primary efficacy measure was the change in pain intensity, assessed by a 10-point NRS, from baseline to 28 days (T28). Changes in cognitive state, daily… Expand