P3 recordings in patients with bilateral temporal lobe lesions.


We recorded event-related potentials to an acoustic "oddball" paradigm from 19 scalp derivations in five patients (three women and two men; age range, 44 to 56) who had global amnesia following encephalitis. CT and MRI showed severe bilateral lesions of anterior and midtemporal lobes. A P3 component, with a peak latency within the normal limits for age-matched controls, was recorded to "target" stimuli in four patients from all leads except Fp1, Fp2, F7, F8, T3, and T4. In the fifth patient, the P3 peak was delayed.


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@article{Onofrj1992P3RI, title={P3 recordings in patients with bilateral temporal lobe lesions.}, author={Marco Onofrj and Tommaso Fulgente and D Nobilio and Goffredo Malatesta and Salvatore Bazzano and P Colamartino and Domenico Gambi}, journal={Neurology}, year={1992}, volume={42 9}, pages={1762-7} }