P3 Abnormality in fragile X syndrome

  title={P3 Abnormality in fragile X syndrome},
  author={David St Clair and Douglas H. R. Blackwood and Chris J. Oliver and Paul Dickens},
  journal={Biological Psychiatry},
P300 (P3) and other long latency auditory event-related potentials (ERPs) were recorded in 33 adults with fragile X syndrome. All patients had an abnormal P3. It was longer in latency and smaller in amplitude than in controls. In several cases, it was split into two separate components, and in others, was generated in response to expected as well as unexpected events. Abnormal P3 was not related to age, percentage cell fragility, or intellectual ability, but complete splitting was associated… CONTINUE READING
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