P2X7 receptor modulation of the viability of radial glial clone L2.3 cells during hypoxic-ischemic brain injury.

Abstract

The purinergic P2X7 receptor (P2X7R) can be activated by ATP and plays significant and complex roles in neuropathology. However, research is limited concerning the role of P2X7R in radial glia following hypoxia-ischemia (HI). In this study, radial glial clone L2.3 cells were cultured and subjected to oxygen-glucose deprivation (OGD) to generate an HI model… (More)
DOI: 10.3892/mmr.2012.816

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