P2X7 receptor expression after ischemia in the cerebral cortex of rats.

@article{Franke2004P2X7RE,
  title={P2X7 receptor expression after ischemia in the cerebral cortex of rats.},
  author={Heike Franke and Albrecht Guenther and J. Grosche and Renate H Schmidt and Steffen Ro{\ss}ner and Robert B. Reinhardt and Heidi Faber-Zuschratter and Dietmar Schneider and Peter Illes},
  journal={Journal of neuropathology and experimental neurology},
  year={2004},
  volume={63 7},
  pages={
          686-99
        }
}
Large amounts of adenosine 5'-triphosphate (ATP) released from cellular sources under pathological conditions such as ischemia may activate purinoceptors of the P2X and P2Y types. In the present study, the expression of the P2X7 receptor-subtype in the brain cortex of spontaneously hypertensive rats was investigated using a permanent focal cerebral ischemia model. Immunocytochemistry with antibodies raised against the intracellular C-terminus of the P2X7 receptor showed a time-dependent… CONTINUE READING

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Character - ization of P 2 X 7 receptors in rat brain after ischemic damage - a combined in vitro and in vivo study

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Characterization of P2X7 receptors in rat brain after ischemic damage - a combined in vitro and in vivo study. Naunyn-Schmiedeberg’s Arch Pharmacol 2003;367:R36

  • A Günther, R Reinhardt, P Schneider, P Illes, H. Franke
  • 2003
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