P2X7 receptor activation-induced contraction and lysis in human saphenous vein smooth muscle.

@article{CarioToumaniantz1998P2X7RA,
  title={P2X7 receptor activation-induced contraction and lysis in human saphenous vein smooth muscle.},
  author={C Cario-Toumaniantz and Gervaise Loirand and Annie Ladoux and Pierre Pacaud},
  journal={Circulation research},
  year={1998},
  volume={83 2},
  pages={196-203}
}
In cutaneous veins where purinergic neurotransmission is more prominent compared with in deep vessels, physiological and pathological roles of nerve-released ATP have been described. Neuronally released ATP has been reported to act through activation of unidentified ionotropic P2X receptor(s). This study analyzed P2X receptor subtypes expressed in human saphenous vein smooth muscle and their physiological functions. Transcripts for both hP2X1 receptors, already identified in other smooth… CONTINUE READING