P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin

@inproceedings{Toulm2010P2X4RI,
  title={P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin},
  author={Estelle Toulm{\'e} and Angie Garcia and Damien S. K. Samways and Terrance M. Egan and Monica J. Carson and Baljit S. Khakh},
  booktitle={The Journal of general physiology},
  year={2010}
}
We investigated the properties and regulation of P2X receptors in immortalized C8-B4 cells of cerebellar microglial origin. Resting C8-B4 cells expressed virtually no functional P2X receptors, but largely increased functional expression of P2X4 receptors within 2-6 h of entering the activated state. Using real-time polymerase chain reaction, we found that P2X4 transcripts were increased during the activated state by 2.4-fold, but this increase was not reflected by a parallel increase in total… CONTINUE READING

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