P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injury.

@article{Cheng2014P2X4RE,
  title={P2X4 receptors expressed on microglial cells in post-ischemic inflammation of brain ischemic injury.},
  author={Rui-dong Cheng and Jing-jing Ren and Yong-Sheng Zhang and Xiang-ming Ye},
  journal={Neurochemistry international},
  year={2014},
  volume={67},
  pages={9-13}
}
Post-ischemic inflammation is an essential step in the progression of brain ischemia injury. P2X4 receptors are the predominant purinergic P2X receptor subtypes expressed on immune and neural cells. The subtype traffic between intracellular compartments and the plasma membrane form protein interactions with each other to regulate ATP-dependent signaling. The P2X4 receptors expressed on microglial cells have been reported to be involved in the inflammatory response of many central nervous system… CONTINUE READING