P2P-R protein localizes to the nucleolus of interphase cells and the periphery of chromosomes in mitotic cells which show maximum P2P-R immunoreactivity.

@article{Gao2002P2PRPL,
  title={P2P-R protein localizes to the nucleolus of interphase cells and the periphery of chromosomes in mitotic cells which show maximum P2P-R immunoreactivity.},
  author={Sizhi Gao and Michael M Witte and Robert E. Scott},
  journal={Journal of cellular physiology},
  year={2002},
  volume={191 2},
  pages={145-54}
}
P2P-R is a nuclear protein that can bind both p53 and Rb1. Its functions include roles in the control of RNA metabolism, apoptosis, and p53-dependent transcription. The expression of P2P-R also is repressed in G1 arrested terminally differentiated cells. The current studies therefore evaluated if P2P-R undergoes cell cycle-associated changes in its abundance and/or localization. Western blots show that relative to G0 quiescent cells, P2P-R protein levels are higher in populations of G2/M cells… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Naturally occurring B-cell responses to breast cancer

Cancer Immunology, Immunotherapy • 2003
View 8 Excerpts
Highly Influenced

De-regulation of the RBBP6 isoform 3/DWNN in human cancers

Molecular and Cellular Biochemistry • 2011
View 3 Excerpts

Similar Papers

Loading similar papers…