P2 receptor expression profiles in human vascular smooth muscle and endothelial cells.

@article{Wang2002P2RE,
  title={P2 receptor expression profiles in human vascular smooth muscle and endothelial cells.},
  author={Lingwei Wang and Lena Karlsson and Sara Moses and Anna Hultg{\aa}rdh-Nilsson and Maria Andersson and Catharina Borna and T{\'o}mas Gudbjartsson and Sverker Jern and David Erlinge},
  journal={Journal of cardiovascular pharmacology},
  year={2002},
  volume={40 6},
  pages={841-53}
}
P2 receptors mediate the actions of the extracellular nucleotides ATP, ADP, UTP, and UDP, regulating several physiologic responses including cardiac function, vascular tone, smooth muscle cell (SMC) proliferation, platelet aggregation, and the release of endothelial factors. P2 receptor characterization has been hampered by the lack of selective antagonists. The aim of the current study was to investigate the mRNA and protein expression of P2X and P2Y receptors in human SMC and in endothelial… CONTINUE READING
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