P19 cells differentiate into glutamatergic and glutamate-responsive neurons in vitro.

@article{Macpherson1997P19CD,
  title={P19 cells differentiate into glutamatergic and glutamate-responsive neurons in vitro.},
  author={P. A. Macpherson and Susan J. Jones and Pat Pawson and Kenneth C Marshall and Michael W McBurney},
  journal={Neuroscience},
  year={1997},
  volume={80 2},
  pages={487-99}
}
The neurotransmitter L-glutamate has been associated with a number of developmental events within the central nervous system including synaptogenesis and the refinement of topographically ordered neural maps. As a model for studying such events at the molecular level, we have examined the expression of glutamate and glutamate receptors in neurons that develop from P19 cells in response to retinoids. We report here that many P19-derived neurons do contain glutamate in secretory vesicles and that… CONTINUE READING
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