P16 alterations increase the metastatic potential of endometrial carcinoma.

@article{Ignatov2008P16AI,
  title={P16 alterations increase the metastatic potential of endometrial carcinoma.},
  author={Atanas Ignatov and Joachim Bischoff and Christa Schwarzenau and Thomas Krebs and D{\"o}rthe K{\"u}ster and Kerstin Herrmann and Serban Dan Costa and Albert Roessner and Andrzej Semczuk and Regine Schneider-Stock},
  journal={Gynecologic oncology},
  year={2008},
  volume={111 2},
  pages={365-71}
}
OBJECTIVE The aim of this study was to investigate the role of p16 in tumorigenesis of endometrial carcinoma (EC). METHODS Expression of p16 protein was analyzed using immunohistochemistry. The methylation status of p16 promoter region was determined by methylation-specific PCR. Deletion analysis of the p16 gene was performed by PCR-analyses. RESULTS… CONTINUE READING