P16-15. Epitope mapping of HIV-specific CD8+ T-cells responses by polyfunctional and proliferation responses reveal distinct specificity defined by function

Background Recent failures of HIV vaccine candidates aimed at inducing protective cellular immunity highlight our need to better characterize responses that are effective in slowing progression to AIDS. Previous work demonstrates that HIV infected subjects who experience slower disease progression maintain better HIV-specific CD8+ T-cell proliferation and… CONTINUE READING