P120 catenin is required for thickening of Schwann cell myelin.

@article{PerrinTricaud2007P120CI,
  title={P120 catenin is required for thickening of Schwann cell myelin.},
  author={Claire Perrin-Tricaud and Urs Rutishauser and Nicolas Tricaud},
  journal={Molecular and cellular neurosciences},
  year={2007},
  volume={35 1},
  pages={120-9}
}
Schwann cell myelin is comprised of compacted membrane regions and cytoplasmic regions with non-compacted membrane. While adherens junctions (AJ) are abundant in non-compact regions, their role in the myelination process is largely undefined. To explore this issue, a small inhibitory hairpin RNA directed against p120ctn has been delivered using adenovirus infection of Schwann cells at early stages of myelination in vivo. With strong and specific reduction in p120ctn levels for over 2 months, (a… CONTINUE READING