P09-14. Emergence of b12 resistant rapidly replication HIV-1 variants during natural infection in the absence of humoral or cellular immune pressure

@article{Bunnik2009P0914EO,
  title={P09-14. Emergence of b12 resistant rapidly replication HIV-1 variants during natural infection in the absence of humoral or cellular immune pressure},
  author={Evelien M. Bunnik and Marilie S D Lobbrecht and Linaida Pisas and Ad van Nuenen and Hanneke Schuitemaker},
  journal={Retrovirology},
  year={2009},
  volume={6},
  pages={P127 - P127}
}
Background Previously we identified patient H19659 who early in his progressive course of infection had HIV-1 variants that were relatively sensitive to neutralization by b12, but who later in infection developed viruses that were highly resistant to b12 neutralization. This increased b12 resistance coincided with an increase in viral replicative capacity… CONTINUE READING