P07-06. HIV-1 transmission and early evolution: whole genome analysis

@article{Herbeck2009P0706HT,
  title={P07-06. HIV-1 transmission and early evolution: whole genome analysis},
  author={JT Herbeck and M Rolland and Weitian Deng and A. C. Collier and J I Mullins},
  journal={Retrovirology},
  year={2009},
  volume={6},
  pages={P104 - P104}
}
Results Comparison between index and seroconverter sequences showed that the dominant HIV-1 variant in the index partner was not necessarily the founder variant in the seroconverter. While HIV-1 infection was established by 2 variants in 2 individuals, 7 individuals presented single founding variants, which showed remarkably homogeneous viral population at the earliest time-points. Intrapatient viral diversity accumulated gradually in all individuals. Given the rapid population growth that… CONTINUE READING

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