P.746 New types of activity of the BDNF dipeptide mimetic: An psychostimulant, anti-opioid and anti-craving effects in opiate dependent rodents

@article{Konstantinopolsky2019P746NT,
  title={P.746 New types of activity of the BDNF dipeptide mimetic: An psychostimulant, anti-opioid and anti-craving effects in opiate dependent rodents},
  author={M. A. Konstantinopolsky and T. A. Gudasheva and L. G. Kolik},
  journal={European Neuropsychopharmacology},
  year={2019},
  volume={29}
}
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References

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Design and synthesis of dipeptide mimetics of the brain-derived neurotrophic factor
TLDR
Low-molecular-weight mimetics of loops 1 and 4 of the brain-derived neurotrophic factor (BDNF) have been designed and synthesized and may form the basis for the design of a novel group of drugs with antidepressant and neuroprotective activities.
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The obtained data suggest that afobazole can be considered as potential effective drug for the correction of various clinical symptoms of morphine withdrawal syndrome.