P-selectin as a candidate target in atherosclerosis.

@article{Molenaar2003PselectinAA,
  title={P-selectin as a candidate target in atherosclerosis.},
  author={T. Molenaar and J. Twisk and Sonja A M de Haas and N. Peterse and Bram J C P Vogelaar and S. H. van Leeuwen and I. Michon and T. V. van Berkel and J. Kuiper and E. Biessen},
  journal={Biochemical pharmacology},
  year={2003},
  volume={66 5},
  pages={
          859-66
        }
}
P-selectin is of critical importance in early atherogenesis by initiating leukocyte rolling at the site of endothelial injury. In order to validate P-selectin as a candidate target for the development of anti-atherogenic strategies, we wanted to obtain quantitative information on P-selectin expression, and identify novel peptide-based lead structures that interact with P-selectin. P-selectin mRNA expression in the aortic arch and in other tissues of apoE-deficient (apoE-/-) mice was determined… Expand
The emerging value of P-selectin as a disease marker
[P-selectin and its role in some diseases].
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CTHRSSVVC Peptide as a Possible Early Molecular Imaging Target for Atherosclerosis
NF-kB activity-dependent P-selectin involved in ox-LDL-induced foam cell formation in U937 cell.
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