P-glycoprotein and multidrug resistance associated protein-1 activity in 132 acute myeloid leukemias according to FAB subtypes and cytogenetics risk groups.

@article{Legrand2004PglycoproteinAM,
  title={P-glycoprotein and multidrug resistance associated protein-1 activity in 132 acute myeloid leukemias according to FAB subtypes and cytogenetics risk groups.},
  author={Ollivier Legrand and Simona Zompi and J B Perrot and Anne-Marie Faussat and Zineb Benderra and Driss Chaoui and Jean-Pierre Marie},
  journal={Haematologica},
  year={2004},
  volume={89 1},
  pages={34-41}
}
BACKGROUND AND OBJECTIVES We studied the function of both Pgp and MRP1 to identify subgroups of patients who could benefit from Pgp reversion, and to clarify in different FAB subtypes and in cytogenetic risk groups their expression and function. DESIGN AND METHODS We examined 132 adults with de novo acute myeloid leukemia (AML) for Pgp and MRP1 expression… CONTINUE READING