P-glycoprotein and metallothionein expression and resistance to chemotherapy in osteosarcoma.

Abstract

The expression of the drug resistance (DR) mediators P-glycoprotein (P-gp) and the metallothioneins (MT) was assessed immunohistochemically in biopsy material from patients with high-grade malignant osteosarcoma (OS). No significant difference was found in survival rate between expressors of both P-gp and MT and non-expressors. Thus, it was concluded that… (More)
DOI: 10.1038/bjc.1998.573

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@article{Shnyder1998PglycoproteinAM, title={P-glycoprotein and metallothionein expression and resistance to chemotherapy in osteosarcoma.}, author={Steve D. Shnyder and Andrew J. Hayes and Joshua Pringle and Cynthia Archer}, journal={British Journal of Cancer}, year={1998}, volume={78}, pages={757 - 759} }