P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

@article{Bellen1989PelementmediatedED,
  title={P-element-mediated enhancer detection: a versatile method to study development in Drosophila.},
  author={Hugo J. Bellen and Cahir J O'Kane and Cathal Wilson and Ueli Grossniklaus and R. K. Pearson and W. J. Gehring},
  journal={Genes & development},
  year={1989},
  volume={3 9},
  pages={1288-300}
}
We generated and characterized greater than 500 Drosophila strains that carry single copies of a novel P-element enhancer detector. In the majority of the strains, the beta-galactosidase reporter gene in the P-transposon responds to nearby transcriptional regulatory sequences in the genome. A remarkable diversity of spatially and temporally regulated… CONTINUE READING