P element insertions and rearrangements at the singed locus of Drosophila melanogaster.

@article{Roiha1988PEI,
  title={P element insertions and rearrangements at the singed locus of Drosophila melanogaster.},
  author={Heli Roiha and Gerald M. Rubin and K. O'Hare},
  journal={Genetics},
  year={1988},
  volume={119 1},
  pages={75-83}
}
DNA from the singed gene of Drosophila melanogaster was isolated using an inversion between a previously cloned P element at cytological location 17C and the hypermutable allele singed-weak. Five out of nine singed mutants examined have alterations in their DNA maps in this region. The singed locus is a hotspot for mutation during P-M hybrid dysgenesis, and we have analyzed 22 mutations induced by P-M hybrid dysgenesis. All 22 have a P element inserted within a 700-bp region. The precise… CONTINUE READING

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