P-chlorophenylalanine increases glutamate receptor 1 transcription in rat amygdala.


The amygdala is a key limbic structure strongly implicated in both epilepsy and anxiety disorders. Epilepsy-like mechanisms involve an increased glutamatergic activity, whereas disturbances in serotonin [5-hydroxytryptamine (5-HT)] systems are associated with anxiety-like behavior. Previous studies suggest that low 5-HT increases amygdala excitability, but… (More)
DOI: 10.1097/WNR.0b013e32834ae2a1


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