Corpus ID: 14778083

P ATERNAL I NHERITANCE OF M ITOCHONDRIAL DNA

@inproceedings{Chwartz2002PAI,
  title={P ATERNAL I NHERITANCE OF M ITOCHONDRIAL DNA},
  author={M. A. S. Chwartz and J. O. V. Issing},
  year={2002}
}
AMMALIAN mitochondrial DNA (mtDNA) is thought to be strictly maternally inherited. 1,2 Sperm mitochondria disappear in early embryogenesis by selective destruction, inactivation, or simple dilution by the vast surplus of oocyte mitochondria. 3 Very small amounts of paternally inherited mtDNA have been detected by the polymerase chain reaction (PCR) in mice after several generations of interspecif-ic backcrosses. 4 Studies of such hybrids and of mouse oocytes microinjected with sperm support the… Expand

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