P 53 EXPRESSION AS A PROGNOSTIC MARKER IN HEPATOCELLULAR CARCINOMA

@inproceedings{Cioca2014P5E,
  title={P 53 EXPRESSION AS A PROGNOSTIC MARKER IN HEPATOCELLULAR CARCINOMA},
  author={Andreea Cioca and Anca Maria C{\^i}mpean and Nilima Rajpal Kundnani and Raluca Amalia Ceaușu and Cristian Suciu and Marius Raica},
  year={2014}
}
Hepatocellular carcinoma (HCC) is one of the most frequent cancers worldwide with a high mortality. Immunohistochemical overexpression of the p53 protein was correlated with a poor prognosis in various human malignancies, including HCC. In our study, 45 resected HCCs were examined to evaluate the expression of p53 and its correlation with clinicopathological parameters. Immunohistochemical detection of p53 with monoclonal human antibody, revealed its overexpression in 20 tumors (44%), including… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 25 REFERENCES

Prognostic Significance of p53 Overexpression after Hepatic Resection of Hepatocellular Carcinoma

C. O. Sung, Yoo, +3 authors C. K. Park
  • The Korean Journal of Gastroenterology 45(6), 425-30.
  • 2005
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Absence of p 53 mutations in hepato - carcinomas from a Mediterranean area of Spain ;

J. Boix-Ferrero, A. Pellin, R. Blesa, M. Adrados
  • Virchows Archives
  • 1999
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Immunohistochemical analysis of p53 overexpression in liver cell dysplasia and in hepatocellular carcinoma

M. Zhao, Z. X. Zhang, J. A. Laissue, A. Zimmerman
  • Virchows Archives
  • 1994
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

Expression of p53 gene in 184 unifocal hepatocellular

Hsu, H-C, +6 authors S-Y
  • 1993
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL