P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate.

@article{Kitada1987P450HA,
  title={P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate.},
  author={Mitsukazu Kitada and Tetsuya Kamataki and Koshiro Itahashi and Tadaaki Rikihisa and Y Kanakubo},
  journal={The Journal of biological chemistry},
  year={1987},
  volume={262 28},
  pages={13534-7}
}
In a reconstituted system containing NADPH, dilauroyl-L-3-phosphatidylcholine, and NADPH-cytochrome P-450 reductase purified from rat liver microsomes, cytochrome P-450 (P-450 HFLa) purified from human fetal livers catalyzed the 16 alpha-hydroxylation of dehydroepiandrosterone 3-sulfate (DHEA-sulfate). Addition of cytochrome b5 purified from rat liver… CONTINUE READING