P‐selectin is up‐regulated in vital organs during murine traumatic shock

@article{Armstead1997PselectinIU,
  title={P‐selectin is up‐regulated in vital organs during murine traumatic shock},
  author={V E Armstead and Alexander G. Minchenko and B J Campbell and Allan M. Lefer},
  journal={The FASEB Journal},
  year={1997},
  volume={11},
  pages={1271 - 1279}
}
Murine traumatic shock is associated with increased adherence of neutrophils to the vascular endothelium resulting in neutrophil infiltration and tissue damage. We examined the effects of trauma on the expression of the adhesion molecule P‐selectin in several vital organs (i.e., heart, lungs, liver, kidneys, and small intestine) 2 h after induction of Noble‐Collip drum trauma in anesthetized rats. Total RNA was extracted from these organs and P‐selectin mRNA was quantified by RNase protection… Expand
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