Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids.

@article{Haddad1996OzoneIO,
  title={Ozone induction of cytokine-induced neutrophil chemoattractant (CINC) and nuclear factor-kappa b in rat lung: inhibition by corticosteroids.},
  author={E B Haddad and Michael Salmon and Hiroshi Koto and Peter J Barnes and Ian M. Adcock and Kian Fan Chung},
  journal={FEBS letters},
  year={1996},
  volume={379 3},
  pages={265-8}
}
We determined in rat lung whether ozone exposure was associated with the expression of the chemokine, cytokine-induced neutrophil chemoattractant (CINC), and of the transcription factor, NF-kappa B. CINC mRNA expression peaked at 2 h after cessation of ozone exposure, and returned to basal levels by 24 h. DNA-binding activity of NF-kappa B showed a marked… CONTINUE READING