Ozone Therapy and Its Use in Medicine

@article{Re2016OzoneTA,
  title={Ozone Therapy and Its Use in Medicine},
  author={Lamberto Re and Robert Jay Rowen and Valter Travagli},
  journal={Cardiology},
  year={2016},
  volume={134},
  pages={99 - 100}
}
This is not relevant to in vivo water consumption. Furthermore, the authors may not have been aware that ozone therapy enhances prostacyclin synthesis and improves the prostacyclin/thromboxane ratio [3] . These effects stand in direct contradiction to the conclusion rendered by the authors of the single report, wherein an improvement in prostacyclin would be expected to have cardioprotective effects: ‘We assume that PGI2 stimulation may contribute to the beneficial effects of ozone treatment… 
Ozone Therapy and Its Use in Medicine: Dr. Jekyll or Mr. Hyde?
TLDR
The authors emphasized that the time period between ozone treatment and the first symptom occurrence of the of acute coronary syndrome seems to be too long to rationally explain it as a consequence of the ozone treatment.
Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain
Ozone, one of the most important air pollutants, is a triatomic molecule containing three atoms of oxygen that results in an unstable form due to its mesomeric structure. It has been well‐known that
Ozone Therapy and Its Use in Medicine: Further Comments
TLDR
It is really not elegant to describe or suggest that an event which occurred long after a treatment to be its obvious side effect, or to question whether or not a standard protocol of autohemotherapy was used.
Positive effect of ozonotherapy on serum concentration of soluble interleukin-2 receptor and neopterin in patients with systemic sclerosis
  • D. Nowicka
  • Medicine
    Postepy dermatologii i alergologii
  • 2019
TLDR
Ozonotherapy had a beneficial influence on the immune response in patients with scleroderma, and Balneotherapy may be considered as an additional therapeutic option, but further research is required.
Formation of Ozonic Compound and Used as Therapeutic Agent in Medicine
It has some encouraging results to use ozone in medicine. However, as ozone is usually in gas state, unstable and strong oxidability, it is difficult to be stored and used commonly. Ozone, ethylene,
Ozonation of Whole Blood Results in an Increased Release of Microparticles from Blood Cells
TLDR
This study is the first to demonstrate that ozone induces a statistically significant increase in the number of microparticles derived from blood and endothelial cells and the changes in some coagulation factors were somewhat mild and did not exceed normal values.
The effectiveness of percutaneous injections of ozonotherapy in low back pain.
TLDR
The researched literature corroborates that, in clinical practice, there is safety in the use of oxygen-ozone therapy through percutaneous injections for the treatment of lumbar pain, especially when compared to surgeries and use of medicines, provided that strict criteria are followed.
Ozonated water lavage and physiological saline irrigation combined with vacuum-sealed drainage in the treatment of 18 cases of chronic osteomyelitis
TLDR
A combination of ozonated water lavage, physiological saline irrigation, and VSD provided good clinical effects in the treatment of chronic osteomyelitis, and thus, is recommended for such treatment.
Ozone injection therapy for intervertebral disc herniation.
TLDR
Current evidence encourage the use of ozone therapy for LBP from LDH, and systematically summarize current evidences, analyze the quantitative available data and investigate the role of percutaneous ozone therapy.
Mechanisms of pathophysiology of blood vessels in patients with multiple sclerosis treated with ozone therapy: a systematic review
TLDR
In this review, the recent literature on the pathophysiology of blood vessels in patients with multiple sclerosis treated with ozone therapy is examined.
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References

SHOWING 1-10 OF 12 REFERENCES
Studies on the biological effects of ozone: 9. Effects of ozone on human platelets
TLDR
It is shown, both by biochemical and morphological criteria, that heparin in the presence of O3 can promote platelet aggregation, and that after Ca(2+) chelation with citrate, Platelet aggregation is much reduced.
Metabolic Response during Impending Myocardial Infarction: II. Clinical Implications
TLDR
There is increasing evidence that high arterial concentrations of FFA can depress myocardial performance by leading to ventricular arrhythmias and decreased contractility, and metabolic intervention in the management of heart attacks should accordingly be directed toward reducing mobilization of adipose tissue FFA and increasing myocardIAL glycolytic activity.
[Clinical assessment of treatment results for atherosclerotic ischemia of the lower extremities with intraarterial ozone injections].
TLDR
The treatment of atherosclerotic ischemia of the lower extremities with O3 is both valuable and safe and showed a significant improvement in both groups manifested by an increase in ankle-arm index, and prolongation of the intermittent claudication distance by more than twice.
Is inappropriate medication use a major cause of adverse drug reactions in the elderly?
TLDR
A good prescription should involve a reduction in the proportion of IMs and should take into consideration the frailty of these patients, as well as the appropriateness of these medications.
Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies.
TLDR
The incidence of serious and fatal adverse drug reactions in US hospitals was found to be extremely high, and data suggest that ADRs represent an important clinical issue.
Myocardial Infarction after Ozone Therapy: Is Ozone Therapy Dr. Jekyll or Mr. Hyde?
We discuss the case of a 46-year-old male patient presenting to the emergency department with acute inferior myocardial infarction. Coronary angiography demonstrated a vasospasm of the left main coron
Studies on the biological effects of ozone: 10. Release of factors from ozonated human platelets.
TLDR
It is shown that significantly higher amount of platelet-derived growth factor (PDGF), transforming growth factor beta1 (TGF-beta1) and interleukin-8 (IL-8) are released in a dose-dependent manner after ozonation of heparinised Platelet-rich plasma samples.
Stud - ies on the biological effects of ozone . 9 . Effects of ozone on human
  • platelets
  • 1999
...
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