Ozonation of ciprofloxacin in water: HRMS identification of reaction products and pathways.

@article{DeWitte2008OzonationOC,
  title={Ozonation of ciprofloxacin in water: HRMS identification of reaction products and pathways.},
  author={Bavo DeWitte and Jo lle Dewulf and Kristof Demeestere and Vincent Van De Vyvere and Patrick De Wispelaere and Herman R Van Langenhove},
  journal={Environmental science & technology},
  year={2008},
  volume={42 13},
  pages={4889-95}
}
Degradation products formed during ozonation of an aqueous solution of the antibiotic ciprofloxacin in a bubble column are analyzed by HPLC-UV high-resolution mass spectrometry. Based on the identification of the reaction products, reaction pathways are proposed starting with (1) degradation at the piperazinyl substituent, (2) degradation at the quinolone… CONTINUE READING